| ncRNA name | hsa-miR-144 |
| ncRNA Category | miRNA |
| Disease name | age-related macular degeneration (AMD) |
| Species | Homo sapiens |
| Tissues/Cell_line | human embryonic stem cells (hESCs) and human-induced pluripotent stem cell (hiPSC)-derived RPE cells |
| Methods | qRT-PCR, immunofluorescence, lentiviral transduction |
| Expression pattern | down-regulated |
| Functional description | We report the detection of hsa-miR-144 as a highly down-regulated microRNA in human RPE cells under high chronic oxidative stress; hsa-miR-144 has multiple NRF2 binding sites in the 3′-UTR and has previously been described to directly regulate its expression in erythrocytes. |
| PubMed ID | 26595608 |
| Year | 2015 |
| Title | Modeling the Dynamic AMD-Associated Chronic Oxidative Stress Changes in Human ESC and iPSC-Derived RPE Cells. |
| Drug-related ncRNA | NO |
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